Molecular Sociology
through in situ structure, assembly and function
News
Parenthood
Posted 11 Jun 2021
Selected Publications (9 first/co-firsts out of 19)
The Molecular Architecture of the Nuclear Basket
Singh, Soni, Hutchings et al. Cell (in print) 2024
Published 28 Mar 2024
Comprehensive structure and functional adaptations of the yeast nuclear pore complex
Akey, Singh, Ouch, Echeverria et al. Cell 2022
Published 03 Jan 2022
A viral genome packaging ring-ATPase is a flexibly coordinated pentamer
Li, Singh et al. Nature Comm. 2021
Published 12 Nov 2021
HSP70 chaperones RNA-free TDP-43 into anisotropic intranuclear liquid spherical shells
Yu et al. Science 2021
Published 05 Feb 2021
Single molecule analysis of effects of non-canonical guide RNAs and specificity-enhancing mutations on Cas9-induced DNA unwinding
Okafor, Singh, Wang et al. Nature Comm. 2021
Published 16 Dec 2019
Real-time observation of DNA target interrogation and product release by the RNA-guided endonuclease CRISPR Cpf1 (Cas12a)
Singh et al. PNAS. 2018
Published 22 May 2018
Mechanisms of improved specificity of engineered Cas9s revealed by single-molecule FRET analysis
Singh et al. Nature Struct Mol Bio. 2018
Published 25 Apr 2018
Understanding the Molecular Mechanisms of the CRISPR Toolbox Using Single Molecule Approaches
Singh et al. ACS Chemical Biology 2018
Published 16 Mar 2018
Real-time observation of DNA recognition and rejection by the RNA-guided endonuclease Cas9
Singh et al. Nature Communications 2016
Published 14 Sep 2016
Determination of in vivo target search kinetics of regulatory noncoding RNA
Fei et al. Science 2015
Published 20 Mar 2015
Posts
Good vs. bad or right vs. wrong
Posted 01 Jan 2018
The worst "favorable" peer-review of all time ?
Posted 15 Jun 2012